Precision medicine aims for personalized prognosis and therapeutics by utilizing recent genome-scale high-throughput profiling techniques, including next-generation sequencing (NGS). However, translating NGS data faces several challenges. First, NGS count data are often overdispersed, requiring appropriate modeling. Second, compared to the number of involved molecules and system complexity, the number of available samples for studying complex disease, such as cancer, is often limited, especially considering disease heterogeneity. The key question is whether we may integrate available data from all different sources or domains to achieve reproducible disease prognosis based on NGS count data. In this paper, we develop a Bayesian Multi-Domain Learning (BMDL) model that derives domain-dependent latent representations of overdispersed count data based on hierarchical negative binomial factorization for accurate cancer subtyping even if the number of samples for a specific cancer type is small. Experimental results from both our simulated and NGS datasets from The Cancer Genome Atlas (TCGA) demonstrate the promising potential of BMDL for effective multi-domain learning without ``negative transfer'' effects often seen in existing multi-task learning and transfer learning methods.

A London doctor controlled robotic surgical arms in Gibraltar to perform prostate cancer telesurgery in near real time from 1,500 miles away.

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Trump's Iran war death toll climbs to 13 after all crew onboard US refueling plane died in crash Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Woman who had years-long romance with Timothee Chalamet says he blindsided her with Kylie Jenner relationship: 'I was in love with him' Airfares have already doubled on key routes and are getting worse - here's when to book to avoid the worst prices They turned on me': JOJO SIWA reveals truth about relationship with Chris Hughes, the horrific abuse she gets from the gay community... and what happened with Mickey Rourke AFTER their Big Brother clash'Comatose' Mojtaba Khamenei'is UNAWARE there is a war on and has no idea he is supreme leader', report says - despite regime issuing his'first statement' Iran-linked cyberattack on US is'first drop of blood' as experts reveal alarming new threat to homeland The astonishing moment Scott Bessent returns to interview noticeably shaken after'Situation Room' call from Trump Recall of cream cheeses upgraded to most serious risk over contamination with deadly bacteria... 'reasonable probability of death' I've spent 25 years treating patients with autism. This is the truth about the condition that many people don't want to hear: DR MAX PEMBERTON Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed I worked with Carolyn Bessette. This is the'messy' truth about what she was REALLY like in secret. After she met JFK Jr she tried to hide it... but we all knew the nighttime gossip Pete Hegseth melts down over'fake headlines' on Strait of Hormuz chaos as US hits Iran with'heaviest' day of fire yet Trump slammed after lifting oil sanctions on Russia as gas prices skyrocket: 'It's a betrayal' And now it turns out you've probably been doing your laundry wrong this entire time. Experts from Which? have revealed the surprising items you should never put in the washing machine.

Trump's Iran war death toll climbs to 13 after all crew onboard US refueling plane died in crash Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back I've spent 25 years treating patients with autism. This is the truth about the condition that many people don't want to hear: DR MAX PEMBERTON'Comatose' Mojtaba Khamenei'is UNAWARE there is a war on and has no idea he is supreme leader', report says - despite regime issuing his'first statement' Iran-linked cyberattack on US is'first drop of blood' as experts reveal alarming new threat to homeland Pete Hegseth melts down over'fake headlines' on Strait of Hormuz chaos as US hits Iran with'heaviest' day of fire yet Formula One set to CANCEL next month's Bahrain and Saudi Arabia races amid war in the Middle East - leaving a month-long gap in the calendar Trump insiders fear Operation Epic Fury is suddenly at risk over a new threat they're struggling to contain: MARK HALPERIN Pete Hegseth challenges Iran's'wounded and disfigured' new Ayatollah to appear on camera I worked with Carolyn Bessette. This is the'messy' truth about what she was REALLY like in secret. After she met JFK Jr she tried to hide it... but we all knew the nighttime gossip The disturbing truth about the link between alcohol and cancer and whether YOU could be at risk... as the Princess of Wales reveals her relationship with drinking has changed since beating the disease NFL fans left divided as team replace historic logo with'boring' new design as part of franchise rebrand Trump slammed after lifting oil sanctions on Russia as gas prices skyrocket: 'It's a betrayal' Friday the 13th linked to biblical end-times prophecy rooted in Jesus' betrayal Friday the 13th and its reputation of bringing bad luck has been tied to an ancient prophecy of global destruction rooted in the betrayal of Jesus Christ. In an oddity of the modern calendar, Friday the 13th has come again, just one month after arriving on February 13, 2026.

'Comatose' Mojtaba Khamenei'is UNAWARE there is a war on and has no idea he is supreme leader', report says - despite regime issuing his'first statement' FBI storms home of Lebanese-born restaurant worker who drove truck filled with explosives into synagogue and opened fire after his'family were killed in airstrike' Trump slammed after lifting oil sanctions on Russia as gas prices skyrocket: 'It's a betrayal' Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Billy Joel's daughter Alexa Ray gives health update amid his battle with rare brain disorder Concerning whispers inside Trump World that Operation Epic Fury is suddenly at risk... and the critical question that will determine how this ends: MARK HALPERIN Meghan Markle masks up to cheer young patients at Los Angeles children's hospital as she agrees deal to sign her latest documentary Beauty queen slams Trump as she's FIRED by White House: 'I stood by you for 20 years... now, I don't even recognize you' Wall Street issues stark warning that Iran oil attacks could wreck Trump's key election promises Truth behind the massacre of 110 school girls in Iran: How shameful episode sparked a deluge of conspiracy theories and lies... as JAKE WALLIS SIMONS explores what really happened Long hair over 45 is ageing and try-hard. I've finally cut mine off. NFL fans left divided as team replace historic logo with'boring' new design as part of franchise rebrand I worked with Carolyn Bessette. This is the'messy' truth about what she was REALLY like in secret. After she met JFK Jr she tried to hide it... but we all knew the nighttime gossip Trump says US is'totally destroying' Iran as he issues chilling threat of more action coming TODAY The 7 types of'hyperarousal' - so, do you get cold sweats or tingling fingers?

What was the topic of your PhD research and why was it an interesting area? My topic of research was developing an optical tactile sensor to track head motion during radiotherapy. I worked on both the hardware and software development of this sensor, though my focus was mostly on the software side. Its importance comes from the fact that during radiotherapy, patients undergoing head and neck cancer treatment are typically immobilised. This is usually done using a thermoplastic mask, which can feel very claustrophobic, or a stereotactic frame.

Modern surgery has gone from long incisions to tiny cuts guided by robots and AI. In the process, however, surgeons have lost something vital: the chance to feel inside the body directly. Without palpation, it becomes harder to detect tissue abnormalities during an operation. A group of surgeons and engineers across Europe is now trying to bring back this vital aspect of surgery. Working within an EU-funded research collaboration called PALPABLE, they are developing a soft robotic "fingertip" that can sense how firm or soft tissue is during minimally invasive and robotic surgery.

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Kentucky mother and daughter turn down $26.5MILLION to sell their farms to secretive tech giant that wants to build data center there Horrifying next twist in the Alexander brothers case: MAUREEN CALLAHAN exposes an unthinkable perversion that's been hiding in plain sight Hollywood icon who starred in Psycho after Hitchcock dubbed her'my new Grace Kelly' looks incredible at 95 Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Tucker Carlson erupts at Trump adviser as she hurls'SLANDER' claim linking him to synagogue shooting Ben Affleck'scores $600m deal' with Netflix to sell his AI film start-up Long hair over 45 is ageing and try-hard. I've finally cut mine off. Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Heartbreaking video shows very elderly DoorDash driver shuffle down customer's driveway with coffee order because he is too poor to retire Amber Valletta, 52, was a '90s Vogue model who made movies with Sandra Bullock and Kate Hudson, see her now Model Cindy Crawford, 60, mocked for her'out of touch' morning routine: 'Nothing about this is normal' A newly surfaced CIA document suggests US intelligence once reviewed research that hinted at a possible cancer treatment more than 60 years ago. The document, produced in February 1951 and declassified in 2014, summarizes a Soviet scientific paper that examined striking similarities between parasitic worms and cancerous tumors. The report describes how researchers believed both organisms thrived under nearly identical metabolic conditions and accumulated large reserves of glycogen, a form of stored energy.